Research Project
ETHEREAL: Personalized Mental Health Disorder Prevention in Adolescents on the Autism Spectrum
Empowering adolescents with Autism Spectrum Disorders (ASD) to self-control the environmental factors for the prevention of mental health disorders.
Where: international
Where: international
Challenge
Noncommunicable Diseases (NCD) account for 80% disease burden in Europe (Source: European Commission). Among them, mental health disorders (MHDs) have a two-way relationship with the other NCDs, since they can either trigger other NCDs or be triggered by them, creating a vicious cycle. Currently, there is no proven interventions for preventing MHD in adolescent with ASD.
Approach
The major risk factors are in-grained in the adolescents biological process. Personalisation done at biological level is the key to prevent their mental states from transitioning to an MHD. Recent research showed how environmental factors can alter gene expressions that lead to an MHD through Epigenetic-Genetic/metabolomic-Mental health process. By leveraging quantitative modelling of this process, ETHEREAL develops a personalised, flexible, single service delivery model that empowers adolescents with ASD to self-monitor their environmental factors and prevent the onset of mental health disorders.
Telemonitoring mobile app analyses and collects vital signs from adolescents on the Autism Spectrum, gathered from sensors, and info about environmental factors, provided by parents and schools through questionnaires. The platform supports the effectiveness of interventions within the community of stakeholders that have an impact on adolescents' lives, including researchers, clinicians and educators. Additionally, the platform supports scientific research community by enabling the collection of data on population with Autism Spectrum Disorder. Engineering is responsible for the design and development of the technological infrastructure that collects data according to standard HL7 FHIR (Fast Healthcare Interoperability Resources) format for the creation of AI models.
The project has received funding from the European Union's Horizon Europe programme, under Grant Agreement No 101095568.
Funded by the European Union. Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union. The European Union cannot be held responsible for them.
Results
Better quality of life
Large quantity of data analysis in adolescents with ASD
Identification of environmental factors
Impacts
Technologies
AI & Data
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